2025
Fermani F, Chang S, Mastrodicasa Y, Peters C, Gaitanos L, Alcala Morales PL, Ramakrishnan C, Deisseroth K, Rüdiger K. Food and water intake are regulated by distinct central amygdala circuits revealed using intersectional genetics. Nature Communications. 16, 1-21 (2025). doi:10.1038/s41467-025-58144-3
Ries C, Stark T, Boulat B, Delling JP, Ruhwedel T, Miralles-Infante A, von Poblotzki J, Ulivi A, von Mücke-Heim IA, Chang S, Sakimura K, Itoi K, Attardo A, Nestvogel D, Czisch M, Nave KA, Moebius W, Dimou L, Deussing JM. Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development. Biorxiv. doi.org/10.1101/2025.02.14.638041.
2024
Chang S*,†, Fermani F†, Huang L, Schneider S, Mathis MW, Deussing JM, Cai N*. Molecular and neural mechanisms of behavioural integration in the extended-amygdala. Biorxiv. www.biorxiv.org/content/10.1101/2024.04.29.591588v1 * Corresponding authors. † Equal contributions. In revision Nature Communications
Fermani F, Chang S, Peters C, Gaitanos L, L. Alcala Morales P, Ramakrishnan C, Deisseroth K, Klein R. Food and water uptake are regulated by distinct central amygdala circuits revealed using intersectional genetics. Biorxiv. doi: doi.org/10.1101/2024.06.22.600182.
Yusupov N, Roeh S, Sotillos Elliott L , Chang S, Loganathan S, Urbina-Treviño L, Fröhlich A, Sauer S, Koedel M, Matosin N, Czamara D, Deussing JM, Binder EB. DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans. Mol Psychiatry. (2024). doi.org/10.1038/s41380-024-02430-x.
2023
Wirth J, Compera N, Yin K, Brood S, Chang S, Martinez-Jimenez CP, Meier M. Spatial transcriptomics using multiplexed deterministic barcoding in tissue. Nature communications. 14, 1523 (2023). doi.org/10.1038/s41467-023-37111-w.
2022
Chang S, Fermani F, Lao CL, Huang L, Jakovcevski M, Giaimo RD, Gagliardi M, Menegaz D, Hennrich AA, Ziller M, Eder M, Klein R, Cai N, Deussing JM. Tripartite extended amygdala - basal ganglia CRH circuit drives locomotor activation and avoidance behaviour. Science Advances. 2022 Nov 18;8(46):eabo1023. doi: 10.1126/sciadv.abo1023.
Chang S, Deussing JM. Corticotropin-Releasing Hormone in the Paraventricular Nucleus of the Hypothalamus—Beyond Hypothalamic–Pituitary–Adrenal Axis Control. Neuroanatomy of Neuroendocrine Systems 12 ed. Switzerland: Springer, Cham; 2022. 231-250p. doi: 10.1007/978-3-030-86630-3_9.
2018
Chang S, Bok P, Tsai CY, Sun CP, Liu H, Deussing JM, Huang GJ. NPTX2 is a key component in the regulation of anxiety. Neuropsychopharmacology. 2018 Aug;43(9):1943-1953. doi: 10.1038/s41386-018-0091-z.
Dedic N, Kühne C, Jakovcevski M, Hartmann J, Genewsky AJ, Gomes KS, Anderzhanova E, Pöhlmann ML, Chang S, Kolarz A, Vogl AM, Dine J, Metzger MW, Schmid B, Almada RC, Ressler KJ, Wotjak CT, Grinevich V, Chen A, Schmidt MV, Wurst W, Refojo D, Deussing JM. Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety. Nat Neurosci. 2018 Jun;21(6):803-807. doi: 10.1038/s41593-018-0151-z.
2016
Chang S, Bok P, Sun CP, Edwards A, Huang GJ. Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress. PLoS Genet. 2016 Oct;12(10):e1006356. doi: 10.1371/journal.pgen.1006356.
2015
Cai N, Li Y, Chang S, Liang J, Lin C, Zhang X, Liang L, Hu J, Chan W, Kendler KS, Malinauskas T, Huang GJ, Li Q, Mott R, Flint J. Genetic Control over mtDNA and Its Relationship to Major Depressive Disorder. Curr Biol. 2015 Dec 21;25(24):3170-7. doi: 10.1016/j.cub.2015.10.065.
Cai N*, Chang S*, Li Y*, Li Q, Hu J, Liang J, Song L, Kretzschmar W, Gan X, Nicod J, Rivera M, Deng H, Du B, Li K, Sang W, Gao J, Gao S, Ha B, Ho HY, Hu C, Hu J, Hu Z, Huang G, Jiang G, Jiang T, Jin W, Li G, Li K, Li Y, Li Y, Li Y, Lin YT, Liu L, Liu T, Liu Y, Liu Y, Lu Y, Lv L, Meng H, Qian P, Sang H, Shen J, Shi J, Sun J, Tao M, Wang G, Wang G, Wang J, Wang L, Wang X, Wang X, Yang H, Yang L, Yin Y, Zhang J, Zhang K, Sun N, Zhang W, Zhang X, Zhang Z, Zhong H, Breen G, Wang J, Marchini J, Chen Y, Xu Q, Xu X, Mott R, Huang GJ, Kendler K, Flint J. Molecular signatures of major depression. Curr Biol. 2015 May 4;25(9):1146-56. doi: 10.1016/j.cub.2015.03.008. *Equal contributions